What is the root cause of diabetes?

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Diabetes mellitus, commonly referred to as diabetes, is a group of metabolic disorders characterized by high blood sugar levels over a prolonged period. The root cause of diabetes varies depending on the type of diabetes:

1. Type 1 Diabetes: This form of diabetes is an autoimmune disorder. The immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the pancreas is unable to produce sufficient insulin, leading to high blood sugar levels. The exact cause of this autoimmune reaction is not entirely understood, but genetic and environmental factors likely play a role.

2. Type 2 Diabetes: The primary cause of type 2 diabetes is insulin resistance. In this condition, the body's cells become less responsive to insulin's action, making it difficult for insulin to transport glucose from the bloodstream into the cells. Consequently, the pancreas may try to compensate by producing more insulin, but over time, it may not keep up with the demand, leading to elevated blood sugar levels. Obesity, sedentary lifestyle, genetic predisposition, and certain ethnic backgrounds are risk factors associated with type 2 diabetes.

3. Gestational Diabetes: This type of diabetes occurs during pregnancy and is thought to result from hormonal changes during gestation, which can lead to insulin resistance. It usually resolves after childbirth, but it may increase the risk of developing type 2 diabetes later in life.

4. Other Types: There are other less common types of diabetes, such as gestational diabetes, maturity-onset diabetes of the young (MODY), and others, each with its own underlying causes.

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